A histidine residue (B), one of the functional groups in the structure of a certain enzyme, has

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A histidine residue (B), one of the functional groups in the structure of a certain enzyme, has a conjugate-acid pKa = 7.8. What is the fraction of each form (BH and B) present at physiological pH (pH = 7.4)?(enzyme) :N CH H B N: + H0 (enzyme) CH :N- H + NH BH (pK = 7.8) + HO

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Organic Chemistry

ISBN: 9781936221349

6th Edition

Authors: Marc Loudon, Jim Parise

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