Synthesis of the herbicide 2,4-D begins with chlorination of phenol followed by reaction of the product with NaOH and chloroacetic acid. Name the chlorinated intermediate, and use resonance structures to explain the pattern of chlorination in the first step.

Transcribed Image Text:

OH Phenol C1₂ OH CI CI 1. CICH₂CO₂H, NaOH 2. H3O+ OCH₂CO₂H CI CI 2,4-D